Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976595 | 0.83 | GBA1 (0.37) | GBA1KDM1AALDH1A1HRH1CYP2D6 | |
| SCHEMBL24844020 | 0.77 | KDM1A (0.36) | GBA1KDM1AALDH1A1HRH1CCR8 | |
| SCHEMBL9976591 | 0.75 | KDM1A (0.39) | GBA1KDM1AALDH1A1HRH1CCR8 | |
| SCHEMBL19844788 | 0.73 | KAT2B (0.41) | GBA1KDM1AALDH1A1KDM2BKAT2B | |
| SCHEMBL20756860 | 0.73 | KCNH2 (0.37) | HRH1CYP2D6 | |
| SCHEMBL20756924 | 0.73 | KAT2B (0.41) | GBA1KDM1AALDH1A1KDM2BKAT2B | |
| SCHEMBL19844789 | 0.73 | KAT2B (0.41) | GBA1KDM1AALDH1A1KDM2BKAT2B | |
| SCHEMBL18872119 | 0.73 | KDM1A (0.38) | GBA1KDM1AALDH1A1HRH1KDM2B | |
| SCHEMBL12423900 | 0.73 | KDM1A (0.40) | GBA1KDM1AALDH1A1HRH1CYP2D6 | |
| SCHEMBL23023334 | 0.72 | GPR119 (0.35) | GBA1KDM1AALDH1A1KDM2BKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4089087-B1 | METHOD FOR PREPARING PYRROLIDINYL UREA DERIVATIVE | ZHANGZHOU PIEN TZE HUANG PHARM (CN) | 2024-07-03 | — | — | EP | disclosed |