Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719489 | 1.00 | TRPV4 (0.41) | TRPV4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30719488 | 1.00 | TRPV4 (0.41) | TRPV4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27346363 | 1.00 | TRPV4 (0.41) | TRPV4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30719538 | 1.00 | TRPV4 (0.41) | TRPV4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30719505 | 1.00 | TRPV4 (0.41) | TRPV4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27346524 | 1.00 | TRPV4 (0.41) | TRPV4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL26064898 | 0.89 | MEN1 (0.43) | TRPV4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25370762 | 0.86 | TRPV4 (0.41) | TRPV4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30719511 | 0.84 | TRPV4 (0.41) | TRPV4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30719498 | 0.84 | TRPV4 (0.41) | TRPV4KDM4ESMN1; SMN2HSD11B1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |