Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | CES2 | O00748 | 3/20 | 0.53 |
| ▸ | CES1 | P23141 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28149563 | 0.98 | KDM4E (0.59) | KDM4ELMNAUSP2ALOX15ALOX12 | |
| SCHEMBL7418675 | 0.98 | KDM4E (0.59) | KDM4ELMNAUSP2ALOX15ALOX12 | |
| SCHEMBL7984521 | 0.98 | KDM4E (0.59) | KDM4ELMNAUSP2ALOX15ALOX12 | |
| SCHEMBL7418674 | 0.98 | KDM4E (0.59) | KDM4ELMNAUSP2ALOX15ALOX12 | |
| SCHEMBL7924687 | 0.98 | KDM4E (0.59) | KDM4ELMNAUSP2ALOX15ALOX12 | |
| SCHEMBL10783627 | 0.98 | KDM4E (0.59) | KDM4ELMNAUSP2ALOX15ALOX12 | |
| SCHEMBL8903696 | 0.98 | KDM4E (0.59) | KDM4ELMNAUSP2ALOX15ALOX12 | |
| SCHEMBL5995590 | 0.98 | KDM4E (0.59) | KDM4ELMNAUSP2ALOX15ALOX12 | |
| SCHEMBL10783630 | 0.98 | KDM4E (0.59) | KDM4ELMNAUSP2ALOX15ALOX12 | |
| SCHEMBL5450436 | 0.94 | PTGS2 (0.53) | KDM4ELMNAUSP2ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308294-C | Substituted acetophenone oxime derivative and preparation process and use thereof | SHANGHAI PESTICIDE INST (CN) | 2007-04-04 | — | — | CN | disclosed |
| CN-1465562-A | Substituted acetophenone oxime derivative and preparation process and use thereof | 上海市农药研究所 | 2004-01-07 | — | — | CN | disclosed |
| CN-1062559-C | 4-aryl oxime ether quinazoline compound and synthesis method and application thereof | UNIV NANKAI (CN) | 2001-02-28 | — | — | CN | disclosed |
| CN-1121071-A | Synthesis and activity of 4-aryl oxime ether quinazoline compound | UNIV NANKAI (CN) | 1996-04-24 | — | — | CN | disclosed |