SCHEMBL27348261

SCHEMBL27348261

CCCCCCCCCCCCCCCCCCCCCCCCCCCCOP(=O)(O)Cc1cc(C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 3/20 0.41
LPAR2 Q9HBW0 5/20 0.41
S1PR2 O95136 3/20 0.41
S1PR1 P21453 3/20 0.41
S1PR3 Q99500 3/20 0.41
ESR1 P03372 1/20 0.41
LPAR3 Q9UBY5 3/20 0.41
LPAR1 Q92633 2/20 0.41
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
SCN2A Q99250 2/20 0.37
NR1I2 O75469 1/20 0.36
GGPS1 O95749 1/20 0.36
CETP P11597 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11289344 1.00 HMGCR (0.41) HMGCRLPAR2S1PR2S1PR1S1PR3
SCHEMBL20139162 1.00 HMGCR (0.41) HMGCRLPAR2S1PR2S1PR1S1PR3
SCHEMBL8869012 0.92 HMGCR (0.48) HMGCRLPAR2LPAR3LPAR1MEN1
SCHEMBL915217 0.92 HMGCR (0.48) HMGCRLPAR2LPAR3LPAR1MEN1
SCHEMBL809384 0.92 HMGCR (0.48) HMGCRLPAR2LPAR3LPAR1MEN1
SCHEMBL28541822 0.92 HMGCR (0.48) HMGCRLPAR2LPAR3LPAR1MEN1
SCHEMBL4247941 0.92 HMGCR (0.48) HMGCRLPAR2LPAR3LPAR1MEN1
SCHEMBL28387496 0.92 HMGCR (0.48) HMGCRLPAR2LPAR3LPAR1MEN1
SCHEMBL8106694 0.91 HMGCR (0.47) HMGCRLPAR2S1PR1S1PR3LPAR3
SCHEMBL39479 0.90 HMGCR (0.41) HMGCRLPAR2S1PR2S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110573566-B High efficiency phosphorus stabilizers based on diphenylamine and heterocyclic diphenylamine derivatives 弗劳恩霍夫应用研究促进协会 2021-07-30 CN disclosed
CN-112585230-A UV curable hot melt adhesive composition for floor application 巴斯夫欧洲公司 2021-03-30 CN disclosed
CN-110573566-A High efficiency phosphorus stabilizers based on diphenylamine and heterocyclic diphenylamine derivatives 弗劳恩霍夫应用研究促进协会 2019-12-13 CN disclosed
CN-1040208-C 3-(2-acyloxyethoxyphenyl) benzofuran-2-ones for use as stabilizers SPECIALTY CHEMICALS HOLDING IN (CH) 1998-10-14 CN disclosed
CN-1087906-A 3-(2-acyloxyethoxyphenyl) benzofuran-2-ones as stabilisers CIBA GEIGY AG (CH) 1994-06-15 CN disclosed