Methacrylic Acid

Methacrylic Acid

SCHEMBL27348264

C=C(C)C(=O)O.ClC=Cc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
AKR1C3 P42330 1/20 0.47
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
PLIN1 O60240 2/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
RECQL P46063 2/20 0.45
PLIN5 Q00G26 2/20 0.45
ABHD5 Q8WTS1 2/20 0.45
ALDH1A1 P00352 2/20 0.45
TNKS O95271 1/20 0.45
HCAR2 Q8TDS4 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC10 Q969S8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27301118 0.88 GLA (0.59) GLATDP1AKR1C3HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL9983047 0.88 GLA (0.59) GLATDP1AKR1C3HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL3017350 0.88 GLA (0.59) GLATDP1AKR1C3HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL3017352 0.88 GLA (0.59) GLATDP1AKR1C3HDAC3HDAC4
SCHEMBL28011333 0.88 GLA (0.48) GLATDP1AKR1C3HDAC3HDAC4
SCHEMBL11864741 0.84 ALDH1A1 (0.48) GLATDP1HDAC3HDAC4HDAC1
Methacrylic Acid SCHEMBL15121420 0.84 MAOB (0.58) GLATDP1AKR1C3HDAC3HDAC4
Methacrylic Acid SCHEMBL1326292 0.82 GLA (0.53) GLATDP1AKR1C3HDAC3HDAC4
SCHEMBL27448226 0.82 GLA (0.44) GLATDP1HDAC3HDAC4HDAC1
Methacrylic Acid SCHEMBL1533293 0.82 GLA (0.53) GLATDP1AKR1C3HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105111367-A Macroporous crosslinked antibacterial macromolecular resin containing halamine functional group, as well as preparation and application thereof UNIV SHANGHAI 2015-12-02 CN disclosed
CN-103193903-A Sterilization polymer containing quaternary ammonium salt and halamine or halamine precursor functional group as well as preparation method and application of sterilization polymer UNIV SHANGHAI 2013-07-10 CN disclosed
CN-102796214-A Bactericidal polymer containing quaternary ammonium salt and halogen amine or halogen amine precursor functional group and preparation method and application thereof UNIV SHANGHAI 2012-11-28 CN disclosed
CN-1086914-C Water insoluble polyquaternary phosphonium salt germicide CHINA PETROCHEMICAL CORP (CN) 2002-07-03 CN disclosed
CN-1086912-C Water insoluble polyquaternary salt germicide CHINA PETROCHEMICAL CORP (CN) 2002-07-03 CN disclosed
CN-1086913-C Water-insoluble disinfectant of poly quaternary salt type CHINA PETROCHEMICAL CORP (CN) 2002-07-03 CN disclosed
CN-1062713-C Insoluble quaternary polyphosphate bactericidal agent and preparation thereof CHINA PETROCHEMICAL CORP (CN) 2001-03-07 CN disclosed
CN-1062712-C Insoluble quaternary polyphosphate bactericidal agent and preparation thereof CHINA PETROCHEMICAL CORP (CN) 2001-03-07 CN disclosed
CN-1062714-C Water insoluble polyquaternary phosphonium salt type germicide CHINA PETROCHEMICAL CORP (CN) 2001-03-07 CN disclosed
CN-1256078-A Water insoluble polyquaternary phosphonium salt germicide CHINA PETROCHEMICAL CORP (CN) 2000-06-14 CN disclosed
CN-1252942-A Water-insoluble disinfectant of poly quaternary salt type CHINA PETROCHEMICAL CORP (CN) 2000-05-17 CN disclosed
CN-1252222-A Water insoluble polyquaternary salt germicide CHINA PETROCHEMICAL CORP (CN) 2000-05-10 CN disclosed
CN-1229588-A Water insoluble polyquaternary phosphonium salt type germicide CHINA PETROCHEMICAL CORP (CN) 1999-09-29 CN disclosed
CN-1209952-A Insoluble quaternary polyphosphate bactericidal agent and preparation thereof CHINA PETROCHEMICAL GEN CORP (CN) 1999-03-10 CN disclosed