SCHEMBL27349403

SCHEMBL27349403

C=CC(=O)OC(=C(CC)C(=C)C#N)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.36
AKT1 P31749 1/20 0.36
ALDH1A1 P00352 8/20 0.35
MAPT P10636 4/20 0.35
THRB P10828 3/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
TSHR P16473 1/20 0.33
THRA P10827 1/20 0.33
LMNA P02545 6/20 0.33
XBP1 P17861 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
ATM Q13315 1/20 0.33
MAPK1 P28482 2/20 0.32
RAB9A P51151 1/20 0.32
ELANE P08246 1/20 0.32
POLB P06746 1/20 0.32
ESR1 P03372 1/20 0.32
PGR P06401 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8034722 0.72 CES2 (0.40) SMN1; SMN2AKT1ALDH1A1MAPTTHRB
SCHEMBL8034719 0.72 CES2 (0.40) SMN1; SMN2AKT1ALDH1A1MAPTTHRB
SCHEMBL11312420 0.70 CES2 (0.41) SMN1; SMN2AKT1ALDH1A1MAPTCES2
SCHEMBL1344602 0.68 AKT1 (0.52) SMN1; SMN2AKT1ALDH1A1MAPTTHRB
SCHEMBL27618130 0.67 AKT1 (0.50) SMN1; SMN2AKT1ALDH1A1MAPTTHRB
Maleic Acid SCHEMBL27864341 0.66 AKT1 (0.46) AKT1ALDH1A1MAPTTHRBCES2
SCHEMBL1053277 0.66 AKT1 (0.54) SMN1; SMN2AKT1ALDH1A1MAPTTHRB
Acrylic Acid Ethyl Ester SCHEMBL30106155 0.66 MAPT (0.44) SMN1; SMN2AKT1ALDH1A1MAPTTHRB
SCHEMBL28857143 0.66 AKT1 (0.48) SMN1; SMN2AKT1ALDH1A1MAPTTHRB
SCHEMBL506075 0.66 AKT1 (0.48) SMN1; SMN2AKT1ALDH1A1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1052023-C Process for the manufacture of low gloss resins GEN ELECTRIC (US) 2000-05-03 CN disclosed
CN-1129719-A Impact modified vinyl chloride resin composition, and graft copolymer compositions GEN ELECTRIC (US) 1996-08-28 CN disclosed
CN-1127762-A Process thermoplastic compositions and emulsion graft copolymer utilizing a polyacid GEN ELECTRIC (US) 1996-07-31 CN disclosed
CN-1104224-A Process for the manufacture of low gloss resins GEN ELECTRIC (US) 1995-06-28 CN disclosed