SCHEMBL27351990

SCHEMBL27351990

C1=CC2=CC=C1C2.CCOCC1CNCCO1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 8/20 0.51
SLC6A2 P23975 6/20 0.51
SLC6A3 Q01959 6/20 0.51
HTR2A P28223 4/20 0.51
HTR2B P41595 2/20 0.51
ADRB2 P07550 2/20 0.51
HTR1A P08908 1/20 0.51
ADRA1A P35348 1/20 0.51
ADRA2C P18825 1/20 0.45
OPRK1 P41145 2/20 0.40
HRH1 P35367 1/20 0.40
OPRD1 P41143 1/20 0.40
HTR3A P46098 1/20 0.40
KCNH2 Q12809 2/20 0.34
MLNR O43193 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2C P28335 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3305237 0.85 SLC6A4 (0.56) SLC6A4SLC6A2SLC6A3HTR2AHTR2B
SCHEMBL30976497 0.85 SLC6A4 (0.56) SLC6A4SLC6A2SLC6A3HTR2AHTR2B
SCHEMBL27985062 0.85 SLC6A4 (0.56) SLC6A4SLC6A2SLC6A3HTR2AHTR2B
SCHEMBL12476117 0.78 SLC6A2 (0.38) SLC6A4SLC6A2SLC6A3HTR2AHTR2B
SCHEMBL27508971 0.78 SLC6A4 (0.38) SLC6A4SLC6A2SLC6A3HTR2AHTR2B
SCHEMBL27365610 0.78 SLC6A2 (0.38) SLC6A4SLC6A2SLC6A3HTR2AHTR2B
SCHEMBL3304900 0.72 HTR2A (0.50) SLC6A4SLC6A2SLC6A3HTR2AHTR2B
SCHEMBL31381393 0.72 TSHR (0.52) SLC6A4SLC6A2SLC6A3HTR2AHTR2B
SCHEMBL3312647 0.72 ALDH1A1 (0.57) SLC6A4SLC6A2SLC6A3HTR2AHTR2B
Hydrochloric Acid SCHEMBL28807544 0.71 SLC6A2 (0.31) SLC6A4SLC6A2SLC6A3HTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1059339-A New quinoline carboxylic acid derivative, the antiseptic-germicide that contains them and their method for making KANEBO LTD (JP) 1992-03-11 CN disclosed