Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | HRH1 | P35367 | 1/20 | 0.73 |
| ▸ | SCN1A | P35498 | 1/20 | 0.73 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.73 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.73 |
| ▸ | NPY2R | P49146 | 4/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787010 | 0.94 | MEN1 (0.62) | LMNAMEN1KMT2ACYP2D6HRH1 | |
| Azacyclonol SCHEMBL241817 | 0.86 | HRH1 (1.00) | LMNAMEN1KMT2ACYP2D6HRH1 | |
| SCHEMBL27960702 | 0.85 | CYP19A1 (0.51) | LMNAMEN1KMT2ACYP2D6HRH1 | |
| SCHEMBL12848015 | 0.85 | CYP19A1 (0.70) | LMNAMEN1KMT2ACYP2D6HRH1 | |
| Azacyclonol SCHEMBL6135637 | 0.84 | HRH1 (0.96) | LMNAMEN1KMT2ACYP2D6HRH1 | |
| Azacyclonol SCHEMBL1890138 | 0.84 | HRH1 (0.96) | LMNAMEN1KMT2ACYP2D6HRH1 | |
| SCHEMBL11831606 | 0.83 | HRH1 (0.81) | LMNAMEN1KMT2ACYP2D6HRH1 | |
| SCHEMBL11832155 | 0.83 | CYP2D6 (0.81) | LMNAMEN1KMT2ACYP2D6HRH1 | |
| Azacyclonol SCHEMBL1648657 | 0.82 | HRH1 (0.93) | LMNAMEN1KMT2ACYP2D6HRH1 | |
| SCHEMBL9253675 | 0.82 | NPY2R (0.57) | LMNAMEN1KMT2ACYP2D6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058780-A | Has the active thiazolidine carboxylic acid amides derivative of anti-allergy, their preparation and application | SANKYO CO (JP) | 1992-02-19 | — | — | CN | disclosed |