Azacyclonol

Azacyclonol

SCHEMBL241817

OC(c1ccccc1)(c1ccccc1)C1CCNCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 3/20 1.00
CYP2D6 P10635 2/20 1.00
LMNA P02545 2/20 1.00
MEN1 O00255 1/20 1.00
SCN1A P35498 1/20 1.00
KMT2A Q03164 1/20 1.00
SCN2A Q99250 1/20 1.00
SCN3A Q9NY46 1/20 1.00
KDM4E B2RXH2 2/20 0.51
NPC1 O15118 1/20 0.51
CYP1A2 P05177 1/20 0.51
HPGD P15428 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP2C19 P33261 1/20 0.51
RAB9A P51151 1/20 0.51
ALDH1A1 P00352 3/20 0.50
CHRM3 P20309 1/20 0.50
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KCNH2 Q12809 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azacyclonol SCHEMBL6135637 0.98 HRH1 (0.96) HRH1CYP2D6LMNAMEN1SCN1A
Azacyclonol SCHEMBL1890138 0.98 HRH1 (0.96) HRH1CYP2D6LMNAMEN1SCN1A
Azacyclonol SCHEMBL1648657 0.96 HRH1 (0.93) HRH1CYP2D6LMNAMEN1SCN1A
Azacyclonol SCHEMBL27517195 0.91 HRH1 (0.83) HRH1CYP2D6LMNAMEN1SCN1A
SCHEMBL11395372 0.91 CYP2D6 (0.83) HRH1CYP2D6LMNAMEN1SCN1A
SCHEMBL11831606 0.90 HRH1 (0.81) HRH1CYP2D6LMNAMEN1SCN1A
SCHEMBL7328353 0.90 CYP2D6 (0.81) HRH1CYP2D6LMNAMEN1SCN1A
SCHEMBL11832155 0.90 CYP2D6 (0.81) HRH1CYP2D6LMNAMEN1SCN1A
SCHEMBL13923571 0.90 HRH1 (0.81) HRH1CYP2D6LMNAMEN1SCN1A
SCHEMBL11835095 0.90 CYP2D6 (0.81) HRH1CYP2D6LMNAMEN1SCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 975 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731194-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP Technologies, Inc. (US) 2026-04-29 EP claimed
EP-4687805-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING ACTIVATED CARBON OR A DERIVATIVE THEREOF CSP Technologies, Inc. (US) 2026-02-11 EP claimed
US-20260027008-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING ACTIVATED CARBON OR A DERIVATIVE THEREOF CSP TECHNOLOGIES, INC. 2026-01-29 US claimed
WO-2025264260-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP TECHNOLOGIES, INC. (US) 2025-12-26 WO claimed
WO-2024263560-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP TECHNOLOGIES, INC. (US) 2024-12-26 WO claimed
WO-2024207016-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING ACTIVATED CARBON OR A DERIVATIVE THEREOF CSP TECHNOLOGIES, INC. (US) 2024-10-03 WO claimed
CN-118561742-A Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof 中国科学院新疆理化技术研究所 2024-08-30 CN claimed
US-20220273600-A1 LITHIUM SALTS OF N-SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2022-09-01 US claimed
EP-3651759-A1 LITHIUM SALTS OF N-SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF Syneurx International (Taiwan) Corp. (TW) 2020-05-20 EP claimed
EP-3635130-A1 PRECISION MEDICINE FOR TREATING AND PREVENTING SUICIDALITY Indiana University Research and Technology Corporation (US) 2020-04-15 EP claimed
WO-2002010115-A1 NEW PROCESSES FOR THE PRODUCTION OF FEXOFENADINE TEXCONTOR ETABLISSEMENT (LI) 2002-02-07 WO claimed
US-6147217-A Synthesis of terfenadine and derivatives SEPRACOR INC. (US) 2000-11-14 US claimed
US-5925761-A Synthesis of terfenadine and derivatives SEPRACOR INC. (US) 1999-07-20 US claimed
US-5777125-A Process for the preparation of tertiary carbinols containing an amino substituent GRUPPO LEPETIT SPA (IT) 1998-07-07 US claimed
EP-0815860-A2 Terfenadine carboxylate and the treatment of allergic disorders SEPRACOR, INC. (US) 1998-01-07 EP claimed
EP-0648759-A1 Antihistaminic compounds, process for their preparation and pharmaceutical compositions containing them ERREGIERRE S.p.A. (IT) 1995-04-19 EP claimed
EP-0641322-A1 PROCESSES FOR PRODUCING $g(a)-PYRIDYL CARBINOLS REILLY INDUSTRIES, INC. (US) 1995-03-08 EP claimed
US-5347006-A Method of preparing a polymorph of terfenadine LAVACCHIELLI AUGUSTO (IT) 1994-09-13 US claimed
WO-1992019596-A2 PROCESSES FOR PRODUCING α-PYRIDYL CARBINOLS REILLY INDUSTRIES, INC. (US) 1992-11-12 WO claimed
US-5043396-A Novel crosslinked polymer having shape memorizing property, method of its use, and molded article having shape memory NIPPON ZEON CO., LTD. (JP) 1991-08-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273600-A1 LITHIUM SALTS OF N-SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF SLC1A2, SLC6A5, SLC1A1 HRH1 809/4885CYP2D6 778/4885LMNA 2385/4885
US-20260027008-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING ACTIVATED CARBON OR A DERIVATIVE THEREOF NOS2, NOS1, NOS3 HRH1 1828/4885CYP2D6 101/4885LMNA 246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.