Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 4/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21580517 | 0.97 | MAOA (0.62) | MAOAHRH1HTR2AHRH3LOXL2 | |
| SCHEMBL6314062 | 0.92 | MAOA (0.54) | MAOAHRH1HTR2AHRH3LOXL2 | |
| SCHEMBL31524115 | 0.92 | HRH3 (0.58) | MAOAHRH1HTR2AHRH3LOXL2 | |
| SCHEMBL3680378 | 0.92 | MAOA (0.75) | MAOAHRH1HTR2AMAOB | |
| SCHEMBL9350714 | 0.89 | MAOA (0.71) | MAOAHRH1HTR2AMAOB | |
| SCHEMBL6312084 | 0.86 | HRH3 (0.58) | MAOAHTR2AHRH3LOXL2ABAT | |
| SCHEMBL3678682 | 0.83 | MAOA (0.62) | MAOAHRH1HTR2ALOXL2 | |
| SCHEMBL12598856 | 0.82 | MAOA (0.95) | MAOAHRH1HTR2ALOXL2MAOB | |
| SCHEMBL2328304 | 0.82 | MAOB (0.67) | MAOAHRH1HTR2ALOXL2MAOB | |
| Hydrochloric Acid SCHEMBL6561599 | 0.80 | MAOA (0.59) | MAOAHRH1HTR2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090581-A | The preparation method of the novel derivative of erythromycin and they and as the application of medicine | ROUSSEL UCLAF (FR) | 1994-08-10 | — | — | CN | claimed |
| CN-1280561-A | Amidocarboxylic acid derivatives | SANKYO CO (JP) | 2001-01-17 | — | — | CN | disclosed |
| CN-1040876-C | New derivatives of erythromycin, their preparation process, their use as medicaments | ROUSSEL UCLAF (FR) | 1998-11-25 | — | — | CN | disclosed |
| CN-1090581-A | The preparation method of the novel derivative of erythromycin and they and as the application of medicine | ROUSSEL UCLAF (FR) | 1994-08-10 | — | — | CN | disclosed |