Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.68 |
| ▸ | PIM1 | P11309 | 1/20 | 0.68 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.68 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268073 | 0.88 | NPC1 (0.85) | PKMNPC1RAB9AKDM4EHTT | |
| SCHEMBL268074 | 0.88 | NPC1 (0.85) | PKMNPC1RAB9AKDM4EHTT | |
| SCHEMBL266882 | 0.87 | MAPT (0.79) | PKMNPC1RAB9AKDM4EHTT | |
| SCHEMBL266884 | 0.87 | MAPT (0.79) | PKMNPC1RAB9AKDM4EHTT | |
| SCHEMBL267011 | 0.86 | PKM (0.81) | PKMNPC1RAB9AKDM4EHTT | |
| SCHEMBL267010 | 0.86 | PKM (0.81) | PKMNPC1RAB9AKDM4EHTT | |
| SCHEMBL268654 | 0.85 | PKM (0.71) | PKMNPC1RAB9AKDM4EHTT | |
| SCHEMBL268931 | 0.85 | NPC1 (0.77) | PKMNPC1RAB9AKDM4EHTT | |
| SCHEMBL268930 | 0.85 | NPC1 (0.77) | PKMNPC1RAB9AKDM4EHTT | |
| SCHEMBL266394 | 0.85 | PKM (0.77) | PKMNPC1RAB9AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |