SCHEMBL27354585

SCHEMBL27354585

Clc1cc(-c2cccc3ccccc23)ccc1Br

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP2C19 P33261 1/20 0.49
RAB9A P51151 1/20 0.49
ATM Q13315 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MCL1 Q07820 2/20 0.45
ACMSD Q8TDX5 1/20 0.45
CA12 O43570 5/20 0.45
CA1 P00915 5/20 0.45
CA2 P00918 5/20 0.45
CA9 Q16790 5/20 0.45
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CYP2A6 P11509 2/20 0.44
ENPP3 O14638 1/20 0.42
ENPP1 P22413 1/20 0.42
AVPR2 P30518 1/20 0.39
AVPR1A P37288 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31602534 0.86 CYP1A2 (0.52) CYP1A2KDM4EALDH1A1CYP2C19RAB9A
SCHEMBL19189329 0.84 CYP1A2 (0.65) CYP1A2KDM4EALDH1A1CYP2C19RAB9A
SCHEMBL27354595 0.82 CYP1A2 (0.51) CYP1A2KDM4EALDH1A1CYP2C19RAB9A
SCHEMBL25501474 0.81 CRHR1 (0.44) CYP1A2KDM4EALDH1A1CYP2C19RAB9A
SCHEMBL26279937 0.80 SERPINE1 (0.42) CYP1A2KDM4EALDH1A1CYP2C19RAB9A
SCHEMBL24748359 0.79 CYP1A2 (0.49) CYP1A2KDM4EALDH1A1CYP2C19RAB9A
SCHEMBL19897387 0.79 CYP1A2 (0.49) CYP1A2KDM4EALDH1A1CYP2C19RAB9A
SCHEMBL25501468 0.79 MCL1 (0.45) KDM4EALDH1A1CYP2C19HSD17B10MCL1
SCHEMBL27355755 0.79 MCL1 (0.47) CYP1A2KDM4EALDH1A1CYP2C19RAB9A
SCHEMBL16792034 0.77 CA12 (0.53) CYP1A2CYP2C19MCL1ACMSDCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025110612-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2025-05-30 WO disclosed
WO-2025110864-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2025-05-30 WO disclosed
WO-2024013275-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-01-18 WO disclosed