SCHEMBL2735487

SCHEMBL2735487

CBOC(C)(C)C(C)(C)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL880119 0.78 THRB (0.32) THRB
SCHEMBL8637 0.75 THRB (0.30) THRB
SCHEMBL24042979 0.75
SCHEMBL9962950 0.73
SCHEMBL20718226 0.73
SCHEMBL20461856 0.73
SCHEMBL14102441 0.73
SCHEMBL17613265 0.71
SCHEMBL5838806 0.71
SCHEMBL6225184 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016169882-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES SYNGENTA PARTICIPATIONS AG (CH) 2016-10-27 WO disclosed
EP-2291371-B1 CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 VITAE PHARMACEUTICALS INC (US) 2015-06-10 EP disclosed
EP-2324017-B1 INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 BOEHRINGER INGELHEIM INT (DE) 2014-12-31 EP disclosed
EP-1937616-B1 NEW BINAPHTHALENE DERIVATIVES, PREPARATION METHOD THEREOF AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2014-12-17 EP disclosed
EP-2774931-A1 PROCESS FOR PRODUCING FUSED-RING AROMATIC COMPOUND, AND CONJUGATED POLYMER Mitsubishi Chemical Corporation (JP) 2014-09-10 EP disclosed
EP-2324018-B1 CYCLIC INHIBITORS OF 11 BETA-HYDROXYSTEROID DEHYDROGENASE 1 BOEHRINGER INGELHEIM INT (DE) 2013-09-04 EP disclosed
WO-2013006738-A1 COMPOUNDS FOR THE TREATMENT OF HIV GILEAD SCIENCES, INC. (US) 2013-01-10 WO disclosed
EP-2253655-B1 Branched polydimethylsiloxane-polyoxyalkyl copolymers, a method for producing same and its use as anti-fumigation additive in UV-hardened silicons EVONIK GOLDSCHMIDT GMBH (DE) 2012-01-04 EP disclosed
EP-2327734-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING ELEMENT UTILIZING SAME Sumitomo Chemical Company, Limited (JP) 2011-06-01 EP disclosed
WO-2009134392-A1 CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 VITAE PHARMACEUTICALS, INC. (US) 2009-11-05 WO disclosed
WO-2009021107-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed
WO-2005056529-A1 CATHEPSIN CYSTEINE PROTEASE INHIBITORS MERCK FROSST CANADA LTD. (CA) 2005-06-23 WO disclosed