⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2735541 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7214922 | 0.97 | — | — | |
| SCHEMBL12607355 | 0.83 | — | — | |
| SCHEMBL2698963 | 0.83 | — | — | |
| SCHEMBL12607353 | 0.83 | — | — | |
| SCHEMBL1337832 | 0.81 | — | — | |
| SCHEMBL29342636 | 0.81 | THRB (0.30) | — | |
| Hydrochloric Acid SCHEMBL1785418 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL13345 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL1785868 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | disclosed |
| CN-116390921-A | Heterocyclic compound with cyclin-dependent kinase inhibition activity, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2023107863-A1 | HETEROCYCLIC COMPOUNDS AS KIT KINASE INHIBITORS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| US-20230167103-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-01 | — | — | US | disclosed |
| EP-4139287-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | disclosed |
| CN-115697979-A | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2023-02-03 | — | — | CN | disclosed |
| US-20230002790-A1 | POLY(Beta-AMINO ESTER) NANOPARTICLES FOR THE NON-VIRAL DELIVERY OF PLASMID DNA FOR GENE EDITING AND RETINAL GENE THERAPY | THE JOHNS HOPKINS UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
| WO-2021214020-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2021-10-28 | — | — | WO | disclosed |
| EP-3828174-A1 | PYRIDAZINONE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| EP-3074389-B1 | QUINOLINE DERIVATIVES AS BROMODOMAIN INHIBITORS | GILEAD SCIENCES INC (US) | 2019-08-14 | — | — | EP | disclosed |
| US-20060025459-A1 | Hydroxyethylamine derivatives for the treatment of alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2006-02-02 | — | — | US | disclosed |
| US-5968907-A | INHIBIT BINDING OF TOXIN TO RECEPTOR OR ORGANISM TO CELL SURFACE RECEPTOR | SYNSORB BIOTECH, INC. (CA) | 1999-10-19 | — | — | US | disclosed |
| US-5965719-A | Combinatorial synthesis of carbohydrate libraries | SUNSORB BIOTECH, INC. (CA) | 1999-10-12 | — | — | US | disclosed |
| EP-0939760-A2 | 1-THIOGALACTOSE DERIVATIVES | SYNSORB Biotech Inc. (CA) | 1999-09-08 | — | — | EP | disclosed |
| EP-0938492-A1 | COMBINATORIAL SYNTHESIS OF CARBOHYDRATE LIBRARIES | SYNSORB Biotech Inc. (CA) | 1999-09-01 | — | — | EP | disclosed |
| EP-0937093-A2 | 1-GALACTOSE DERIVATIVES | SYNSORB Biotech Inc. (CA) | 1999-08-25 | — | — | EP | disclosed |
| US-5932554-A | PREVENT BINDING OF TOXINS TO RECEPTORS | SYNSORB BIOTECH, INC. (CA) | 1999-08-03 | — | — | US | disclosed |
| WO-1998022487-A1 | COMBINATORIAL SYNTHESIS OF CARBOHYDRATE LIBRARIES | SYNSORB BIOTECH, INC. (CA) | 1998-05-28 | — | — | WO | disclosed |
| WO-1998021222-A2 | 1-GALACTOSE DERIVATIVES | SYNSORB BIOTECH, INC. (CA) | 1998-05-22 | — | — | WO | disclosed |
| WO-1998021221-A2 | 1-THIOGALACTOSE DERIVATIVES | SYNSORB BIOTECH, INC. (CA) | 1998-05-22 | — | — | WO | disclosed |