Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928282 | 0.84 | LOXL2 (0.69) | LOXL2SLC7A5HTR2CNR1H2ENPP2 | |
| SCHEMBL27574383 | 0.84 | LOXL2 (0.51) | LOXL2SLC7A5NR1H2NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL2316080 | 0.83 | LOXL2 (0.67) | LOXL2SLC7A5HTR2CNR1H2ENPP2 | |
| SCHEMBL13546226 | 0.80 | SLC7A5 (0.42) | LOXL2SLC7A5ALDH1A1NFKB1SMN1; SMN2 | |
| SCHEMBL27440895 | 0.79 | LOXL2 (0.61) | LOXL2SLC7A5HTR2CNR1H2ENPP2 | |
| SCHEMBL13525145 | 0.78 | TMEM97 (0.44) | SLC7A5CES2CES1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30973065 | 0.78 | PARP1 (0.50) | CES2CES1SMN1; SMN2 | |
| SCHEMBL27294771 | 0.76 | SLC7A5 (0.39) | LOXL2SLC7A5CYP4F2CYP4A11CES2 | |
| SCHEMBL27796426 | 0.76 | LOXL2 (0.65) | LOXL2SLC7A5HTR2CENPP2CFD | |
| SCHEMBL13028737 | 0.76 | LOXL2 (0.60) | LOXL2SLC7A5HTR2CENPP2CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052731-C | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 2000-05-24 | — | — | CN | disclosed |
| CN-1138335-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1996-12-18 | — | — | CN | disclosed |