SCHEMBL2735593

SCHEMBL2735593

CCCCNC(=O)c1ccccc1SC

nearest known ligand 0.91

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.91
KMT2A Q03164 3/20 0.74
HSD17B10 Q99714 1/20 0.74
TSHR P16473 1/20 0.73
HTT P42858 1/20 0.73
GAA P10253 3/20 0.68
ALDH1A1 P00352 2/20 0.68
NAAA Q02083 1/20 0.57
LMNA P02545 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2735595 0.95 HPGD (1.00) HPGDKMT2AHSD17B10TSHRHTT
SCHEMBL8625421 0.94 HPGD (0.97) HPGDKMT2AHSD17B10TSHRHTT
SCHEMBL8620464 0.94 HPGD (0.97) HPGDKMT2AHSD17B10TSHRHTT
SCHEMBL8625385 0.94 HPGD (0.97) HPGDKMT2AHSD17B10TSHRHTT
SCHEMBL12124514 0.94 HPGD (0.97) HPGDKMT2AHSD17B10TSHRHTT
SCHEMBL8625820 0.94 HPGD (0.97) HPGDKMT2AHSD17B10TSHRHTT
SCHEMBL11341066 0.89 TSHR (0.75) HPGDKMT2AHSD17B10TSHRHTT
SCHEMBL30593956 0.89 TSHR (0.75) HPGDKMT2AHSD17B10TSHRHTT
SCHEMBL1387769 0.89 TSHR (0.75) HPGDKMT2AHSD17B10TSHRHTT
SCHEMBL11172438 0.86 TSHR (0.71) HPGDKMT2AHSD17B10TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088884-B2 Multi-armed forms of activated polyoxazoline and methods of synthesis thereof SERINA THERAPEUTICS, INC. (US) 2012-01-03 US disclosed
US-20100249368-A1 Multi-Armed Forms of Activated Polyoxazoline and Methods of Synthesis Thereof SERINA THERAPEUTICS, INC. (US) 2010-09-30 US disclosed