Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NAAA | Q02083 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625385 | 0.98 | HPGD (0.97) | HPGDKMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL8625421 | 0.98 | HPGD (0.97) | HPGDKMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL8625820 | 0.98 | HPGD (0.97) | HPGDKMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL12124514 | 0.98 | HPGD (0.97) | HPGDKMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL8620464 | 0.98 | HPGD (0.97) | HPGDKMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL2735593 | 0.95 | HPGD (0.91) | HPGDKMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL10789563 | 0.88 | HPGD (0.78) | HPGDKMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL11341066 | 0.84 | TSHR (0.75) | HPGDKMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL30593956 | 0.84 | TSHR (0.75) | HPGDKMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL1387769 | 0.84 | TSHR (0.75) | HPGDKMT2AHSD17B10GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088884-B2 | Multi-armed forms of activated polyoxazoline and methods of synthesis thereof | SERINA THERAPEUTICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100249368-A1 | Multi-Armed Forms of Activated Polyoxazoline and Methods of Synthesis Thereof | SERINA THERAPEUTICS, INC. (US) | 2010-09-30 | — | — | US | disclosed |