SCHEMBL27356154

SCHEMBL27356154

O=C(NCc1ccccc1)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 20/20 1.00
DPP9 Q86TI2 20/20 1.00
GLMN Q92990 3/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30685225 1.00 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL27357736 0.93 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL30684983 0.93 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL30684953 0.93 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL30685077 0.89 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL27356164 0.89 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL27357734 0.86 DPP8 (0.76) DPP8DPP9GLMN
SCHEMBL31732567 0.85 DPP9 (1.00) DPP8DPP9GLMN
SCHEMBL30685294 0.85 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL30685179 0.84 DPP8 (1.00) DPP8DPP9GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 WO disclosed