SCHEMBL30685077

SCHEMBL30685077

O=C(NCCCc1ccccc1)OC12CC3CC(CC(NCC(=O)N4Cc5ccccc5C4)(C3)C1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 20/20 1.00
DPP9 Q86TI2 20/20 1.00
GLMN Q92990 3/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27356164 1.00 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL31732567 0.89 DPP9 (1.00) DPP8DPP9GLMN
SCHEMBL30685294 0.89 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL30685225 0.89 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL27356154 0.89 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL27357738 0.87 DPP9 (0.77) DPP8DPP9GLMN
SCHEMBL30684983 0.82 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL30684953 0.82 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL27357736 0.82 DPP8 (1.00) DPP8DPP9GLMN
SCHEMBL30685134 0.82 DPP8 (0.69) DPP8DPP9GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353833-A1 DPP9 BINDING COMPOUNDS UNIV ANTWERPEN (BE) 2025-11-20 US disclosed
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353833-A1 DPP9 BINDING COMPOUNDS DPP9, DPP7, DPP3 DPP8 5/4885DPP9 1/4885GLMN 1309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.