SCHEMBL27356226

SCHEMBL27356226

O=C(CNC12CC3CC4CC(NC(=O)C56CC7CC(CC(C7)C5)C6)(C1)C34C2)N1Cc2ccccc2C1

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ DPP9 Q86TI2 19/20 0.68
▸ DPP8 Q6V1X1 17/20 0.68
▸ GLMN Q92990 2/20 0.58
▸ DPP4 P27487 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30685297 0.81 DPP9 (1.00) DPP9DPP8GLMNDPP4
SCHEMBL27357812 0.80 DPP9 (0.62) DPP9DPP8GLMNDPP4
SCHEMBL27357603 0.76 DPP9 (0.59) DPP9DPP8GLMNDPP4
SCHEMBL30685096 0.72 DPP9 (1.00) DPP9DPP8GLMNDPP4
SCHEMBL30685238 0.72 DPP9 (0.88) DPP9DPP8GLMNDPP4
SCHEMBL30685001 0.70 DPP9 (1.00) DPP9DPP8GLMN
SCHEMBL27356261 0.70 DPP9 (1.00) DPP9DPP8GLMN
SCHEMBL27356218 0.70 DPP9 (0.71) DPP9DPP8GLMNDPP4
SCHEMBL30685008 0.70 DPP9 (1.00) DPP9DPP8GLMNDPP4
SCHEMBL27356198 0.70 DPP9 (1.00) DPP9DPP8GLMNDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
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