SCHEMBL30685238

SCHEMBL30685238

O=C(CNC12CC3CC(CC(O)(C3)C1)C2)N1Cc2ccccc2C1

nearest known ligand 0.88

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP9 Q86TI2 19/20 0.88
DPP8 Q6V1X1 18/20 0.88
GLMN Q92990 2/20 0.88
DPP4 P27487 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL30685151 0.95 DPP9 (0.80) DPP9DPP8GLMNDPP4
SCHEMBL27356198 0.88 DPP9 (1.00) DPP9DPP8GLMNDPP4
SCHEMBL30685008 0.88 DPP9 (1.00) DPP9DPP8GLMNDPP4
SCHEMBL30685096 0.86 DPP9 (1.00) DPP9DPP8GLMNDPP4
SCHEMBL27355961 0.84 DPP9 (1.00) DPP9DPP8GLMN
SCHEMBL30685297 0.84 DPP9 (1.00) DPP9DPP8GLMNDPP4
SCHEMBL31732767 0.82 DPP9 (0.73) DPP9DPP8GLMN
SCHEMBL30685102 0.82 DPP9 (0.77) DPP9DPP8GLMN
SCHEMBL30685103 0.82 DPP9 (0.77) DPP9DPP8GLMN
Trifluoroacetic Acid SCHEMBL30685147 0.81 DPP9 (1.00) DPP9DPP8GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353833-A1 DPP9 BINDING COMPOUNDS UNIV ANTWERPEN (BE) 2025-11-20 US disclosed
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353833-A1 DPP9 BINDING COMPOUNDS DPP9, DPP7, DPP3 DPP9 1/4885DPP8 5/4885GLMN 1309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.