SCHEMBL27356459

SCHEMBL27356459

COC(=O)C(C)NC(=O)OC1(C)CC2CC(C)CC(NCC(=O)N3Cc4ccc(F)cc4C3)(C2)C1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ DPP8 Q6V1X1 20/20 0.56
▸ DPP9 Q86TI2 20/20 0.56
▸ GLMN Q92990 2/20 0.44
▸ DPP4 P27487 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27356404 0.93 DPP8 (0.54) DPP8DPP9GLMNDPP4
SCHEMBL27356463 0.87 DPP8 (0.67) DPP8DPP9GLMN
SCHEMBL30685099 0.87 DPP8 (0.67) DPP8DPP9GLMN
SCHEMBL27356433 0.83 DPP8 (0.46) DPP8DPP9GLMN
SCHEMBL27356064 0.82 DPP9 (0.74) DPP8DPP9GLMN
SCHEMBL27356407 0.79 DPP8 (0.65) DPP8DPP9GLMN
SCHEMBL27356167 0.79 DPP8 (0.75) DPP8DPP9GLMN
SCHEMBL27356085 0.79 DPP9 (0.73) DPP8DPP9GLMN
SCHEMBL30685149 0.78 DPP8 (0.63) DPP8DPP9GLMN
SCHEMBL30685182 0.78 DPP8 (0.62) DPP8DPP9GLMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233024-A1 DPP9 BINDING COMPOUNDS UNIVERSITEIT ANTWERPEN (BE) 2023-12-07 — — WO disclosed
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