Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737375 | 0.77 | MEN1 (0.60) | MEN1KMT2ACNR1CSF1RNTSR1 | |
| SCHEMBL11351339 | 0.77 | OPRK1 (0.48) | CNR1NTSR1OPRK1PDE4DGABRP | |
| SCHEMBL9686843 | 0.76 | MEN1 (0.55) | MEN1KMT2ACNR1CSF1RNTSR1 | |
| SCHEMBL9687276 | 0.76 | MEN1 (0.55) | MEN1KMT2ACNR1CSF1RNTSR1 | |
| Ro-24-7429 SCHEMBL2050520 | 0.75 | MEN1 (0.54) | MEN1KMT2ACNR1CSF1RNTSR1 | |
| SCHEMBL9685497 | 0.75 | MEN1 (0.54) | MEN1KMT2ACNR1CSF1RNTSR1 | |
| SCHEMBL9687273 | 0.75 | MEN1 (0.54) | MEN1KMT2ACNR1CSF1RNTSR1 | |
| Ro-24-7429 SCHEMBL29350777 | 0.75 | MEN1 (0.54) | MEN1KMT2ACNR1CSF1RNTSR1 | |
| SCHEMBL9686189 | 0.74 | MEN1 (0.53) | MEN1KMT2ACNR1NTSR1OPRK1 | |
| SCHEMBL27470590 | 0.73 | CHRM1 (0.51) | OPRK1PDE4DLMNACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916218-A | Methods and materials for treating fibrosis | 斯格本斯眼科研究所有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-102753526-A | Pyridinone hydroxycyclopentyl carboxamides: HIV integrase inhibitors with therapeutic applications | UNIV GEORGIA | 2012-10-24 | — | — | CN | claimed |
| CN-115916218-A | Methods and materials for treating fibrosis | 斯格本斯眼科研究所有限公司 | 2023-04-04 | — | — | CN | disclosed |
| EP-4138853-A1 | METHODS AND MATERIALS FOR TREATMENT OF FIBROSIS | The Schepens Eye Research Institute, Inc. (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-102753526-A | Pyridinone hydroxycyclopentyl carboxamides: HIV integrase inhibitors with therapeutic applications | UNIV GEORGIA | 2012-10-24 | — | — | CN | disclosed |
| CN-1265665-A | Benzimidazole derivatives | GLAXO GROUP LTD (GB) | 2000-09-06 | — | — | CN | disclosed |
| CN-1052010-C | Benzimidazole derivatives, method for the production thereof, use thereof and pharmaceutical preparations containing the same | WELLCOME FOUND (GB) | 2000-05-03 | — | — | CN | disclosed |
| CN-1159194-A | Therapeutic compounds | WELLCOME FOUND (GB) | 1997-09-10 | — | — | CN | disclosed |