Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.45 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL19134066 | 0.85 | ALDH1A1 (0.64) | ALDH1A1FKBP5CYP3A4TSHRGABRA1 | |
| SCHEMBL47208 | 0.85 | — | — | |
| SCHEMBL27531068 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL27259157 | 0.83 | — | — | |
| SCHEMBL28244057 | 0.83 | — | — | |
| Ammonia Solution, Strong SCHEMBL28242555 | 0.83 | — | — | |
| Boric Acid SCHEMBL27881076 | 0.81 | ALDH1A1 (0.80) | ALDH1A1FKBP5CYP3A4TSHRGABRA1 | |
| Dimethylamine SCHEMBL4496394 | 0.80 | — | — | |
| SCHEMBL4302840 | 0.76 | ALDH1A1 (0.80) | ALDH1A1FKBP5CYP3A4NFKB1KDM4E | |
| Butane SCHEMBL28239837 | 0.76 | ALDH1A1 (0.80) | ALDH1A1FKBP5CYP3A4NFKB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060471-C | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 2001-01-10 | — | — | CN | claimed |
| CN-1060470-C | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 2001-01-10 | — | — | CN | claimed |
| CN-1187488-A | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 1998-07-15 | — | — | CN | claimed |
| CN-1187489-A | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 1998-07-15 | — | — | CN | claimed |
| CN-102952078-B | Preparation method of alkyl imidazole carboxylate ionic liquid | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | disclosed |
| CN-1060471-C | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 2001-01-10 | — | — | CN | disclosed |
| CN-1060470-C | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 2001-01-10 | — | — | CN | disclosed |
| CN-1060470-C | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 2001-01-10 | — | — | CN | disclosed |
| CN-1187488-A | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 1998-07-15 | — | — | CN | disclosed |
| CN-1187488-A | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 1998-07-15 | — | — | CN | disclosed |
| CN-1187489-A | Process for preparing 4-methylimidazole | CHINA PETROCHEMICAL CORP (CN) | 1998-07-15 | — | — | CN | disclosed |