Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 15/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 15/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 15/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 15/20 | 0.73 |
| ▸ | HDAC10 | Q969S8 | 15/20 | 0.73 |
| ▸ | HDAC11 | Q96DB2 | 15/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 15/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 15/20 | 0.73 |
| ▸ | HDAC5 | Q9UQL6 | 15/20 | 0.73 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | ASPH | Q12797 | 1/20 | 0.64 |
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214210 | 0.91 | HDAC3 (0.70) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20214211 | 0.91 | HDAC3 (0.70) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20214566 | 0.85 | HDAC1 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19862461 | 0.82 | HDAC1 (0.74) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22018078 | 0.81 | HDAC1 (0.72) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12808803 | 0.79 | HDAC1 (0.81) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Belinostat SCHEMBL29712104 | 0.79 | HDAC1 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Belinostat SCHEMBL375906 | 0.79 | HDAC1 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Belinostat SCHEMBL29379950 | 0.79 | HDAC1 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Belinostat SCHEMBL375656 | 0.79 | HDAC1 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023242278-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | UNIVERSITÄTSMEDIZIN GREIFSWALD (DE) | 2023-12-21 | — | — | WO | disclosed |