Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 18/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 17/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 17/20 | 0.74 |
| ▸ | HDAC7 | Q8WUI4 | 17/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 17/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 17/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 17/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.74 |
| ▸ | HDAC9 | Q9UKV0 | 17/20 | 0.74 |
| ▸ | HDAC5 | Q9UQL6 | 17/20 | 0.74 |
| ▸ | BRD4 | O60885 | 1/20 | 0.74 |
| ▸ | ESR1 | P03372 | 1/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | PDE4A | P27815 | 1/20 | 0.74 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.74 |
| ▸ | HTR6 | P50406 | 1/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.74 |
| ▸ | ASPH | Q12797 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018078 | 0.87 | HDAC1 (0.72) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1402831 | 0.86 | HDAC1 (0.71) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL13029037 | 0.86 | HDAC1 (0.79) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1402835 | 0.86 | HDAC1 (0.71) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| Belinostat SCHEMBL375656 | 0.85 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| Belinostat SCHEMBL29712104 | 0.85 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| Belinostat SCHEMBL375906 | 0.85 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| Belinostat SCHEMBL29379950 | 0.85 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL15457015 | 0.84 | HDAC8 (0.74) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL5960371 | 0.84 | HDAC2 (0.74) | HDAC1HDAC8HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367145-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | UNIVERSITÄTSMEDIZIN GREIFSWALD (DE) | 2025-12-04 | — | — | US | claimed |
| EP-4539835-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | Universitätsmedizin Greifswald (DE) | 2025-04-23 | — | — | EP | claimed |
| WO-2023242278-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | UNIVERSITÄTSMEDIZIN GREIFSWALD (DE) | 2023-12-21 | — | — | WO | claimed |
| EP-4292591-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | Universitätsmedizin Greifswald (DE) | 2023-12-20 | — | — | EP | claimed |
| US-20250367145-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | UNIVERSITÄTSMEDIZIN GREIFSWALD (DE) | 2025-12-04 | — | — | US | disclosed |
| EP-4539835-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | Universitätsmedizin Greifswald (DE) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023242278-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | UNIVERSITÄTSMEDIZIN GREIFSWALD (DE) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023242278-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | UNIVERSITÄTSMEDIZIN GREIFSWALD (DE) | 2023-12-21 | — | — | WO | disclosed |
| EP-4292591-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | Universitätsmedizin Greifswald (DE) | 2023-12-20 | — | — | EP | disclosed |
| WO-2018029699-A1 | SOLID STATE FORMS OF (2E)-N-HYDROXY-3-[3-(PHENYLSULFAMOYL)PHENYL]PROP-2-ENAMIDE AND PROCESS FOR PREPARATION THEREOF | MSN RESEARCH & DEVELOPMENT CENTER (IN) | 2018-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367145-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | REN, SLC10A1, GLS | HDAC1 1068/4885HDAC8 1326/4885HDAC3 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.