Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27359173 | 0.87 | MAPT (0.54) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL3273470 | 0.87 | ALDH1A1 (0.62) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL31008743 | 0.87 | ALDH1A1 (0.58) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL25030409 | 0.86 | MAPT (0.53) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL880700 | 0.86 | CHRM1 (0.55) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL26115468 | 0.84 | MAPT (0.51) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL9093407 | 0.84 | ALDH1A1 (0.56) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL12772860 | 0.84 | CHRM1 (0.56) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL3882849 | 0.83 | MEN1 (0.55) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL26115526 | 0.83 | MAPT (0.50) | MAPTCHRM1ALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217947-A1 | Morpholinylquinazoline Compound, Pharmaceutical compositions thereof and Use Thereof | SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217947-A1 | Morpholinylquinazoline Compound, Pharmaceutical compositions thereof and Use Thereof | HDAC6, HDAC9, HDAC7 | MAPT 1365/4885CHRM1 4687/4885ALDH1A1 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.