Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879703 | 0.82 | KCNH2 (0.37) | GRM5ADORA2AADORA1MEN1CYP3A4 | |
| SCHEMBL25636505 | 0.79 | CCR1 (0.32) | GRM5CYP3A4MAPTHTTRAB9A | |
| SCHEMBL1260062 | 0.79 | TYR (0.41) | TYRTLR8CTRCPDE10AMEN1 | |
| SCHEMBL23341589 | 0.76 | KCNH2 (0.43) | TYRTLR8GRM5CTRCESR1 | |
| SCHEMBL19304422 | 0.76 | TYR (0.43) | TYRTLR8CTRCPDE10AMEN1 | |
| SCHEMBL18455183 | 0.75 | MEN1 (0.32) | MEN1CYP3A4KMT2A | |
| SCHEMBL8326377 | 0.74 | KDM4E (0.42) | MEN1MAPTHTTKMT2ATDP1 | |
| SCHEMBL27360658 | 0.73 | TYR (0.37) | TYRTLR8CTRCPDE10AMEN1 | |
| SCHEMBL27813430 | 0.72 | TYR (0.47) | TYRTLR8ADORA2AESR1MEN1 | |
| SCHEMBL13073819 | 0.70 | GRM5 (0.45) | TLR8GRM5TLR7CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247666-A1 | FLUORESCENT PROBES FOR MAGL | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |