Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.37 |
| ▸ | DNM2 | P50570 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260062 | 0.77 | TYR (0.41) | TYRTLR8CTRCMEN1TP53 | |
| SCHEMBL930276 | 0.76 | CCR1 (0.33) | MEN1MAPTKMT2ANOS2 | |
| SCHEMBL19304422 | 0.74 | TYR (0.43) | TYRTLR8CTRCMEN1TP53 | |
| SCHEMBL27359331 | 0.73 | TYR (0.38) | TYRTLR8CTRCMEN1TP53 | |
| SCHEMBL28207251 | 0.73 | TYR (0.38) | TYRDNM2TLR8CTRCMEN1 | |
| SCHEMBL27813430 | 0.70 | TYR (0.47) | TYRTLR8MEN1TP53CYP3A4 | |
| SCHEMBL15831900 | 0.70 | LATS1 (0.36) | DNM2MEN1MAPTKMT2A | |
| SCHEMBL24609039 | 0.69 | TLR8 (0.53) | TYRTLR8 | |
| Bromide SCHEMBL28825154 | 0.68 | TYR (0.45) | TYRTLR8MEN1TP53CYP3A4 | |
| SCHEMBL4633219 | 0.67 | TYR (0.50) | TYRTLR8CTRCMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247666-A1 | FLUORESCENT PROBES FOR MAGL | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |