Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 20/20 | 0.50 |
| ▸ | ELOC | Q15369 | 6/20 | 0.50 |
| ▸ | ELOB | Q15370 | 6/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360238 | 0.90 | VHL (0.46) | VHLELOCELOB | |
| SCHEMBL24757097 | 0.89 | VHL (0.49) | VHLELOCELOBHDAC3HDAC1 | |
| SCHEMBL24756803 | 0.89 | VHL (0.46) | VHLELOCELOBHDAC3HDAC1 | |
| SCHEMBL27359434 | 0.89 | VHL (0.51) | VHLELOCELOBHDAC3HDAC1 | |
| SCHEMBL30148969 | 0.85 | VHL (0.46) | VHLELOCELOBHDAC3HDAC1 | |
| SCHEMBL22565394 | 0.85 | VHL (0.48) | VHLELOCELOBHDAC3HDAC1 | |
| SCHEMBL22565403 | 0.83 | VHL (0.51) | VHLELOCELOBHDAC3HDAC1 | |
| SCHEMBL22565417 | 0.83 | VHL (0.53) | VHLELOCELOBHDAC3HDAC1 | |
| SCHEMBL26786695 | 0.82 | VHL (0.51) | VHLELOCELOB | |
| SCHEMBL27359850 | 0.82 | VHL (0.49) | VHLELOCELOBHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |