Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 3/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361068 | 0.98 | TSHR (0.55) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL29066452 | 0.88 | TSHR (0.50) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL578128 | 0.86 | TSHR (0.77) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL2697097 | 0.85 | ALDH1A1 (0.59) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL27559699 | 0.85 | TSHR (0.57) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL1816651 | 0.83 | TSHR (0.64) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL7670783 | 0.83 | TSHR (0.71) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL9279757 | 0.83 | ALDH1A1 (0.79) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL27887742 | 0.82 | TSHR (0.84) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL30455175 | 0.82 | TSHR (0.62) | TSHRALDH1A1TDP1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351453-A | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-01-21 | — | — | CN | disclosed |
| CN-100366605-C | Compounds to treat alzheimer's disease | ELAN PHARM INC (US) | 2008-02-06 | — | — | CN | disclosed |
| CN-1976907-A | Heterocyclic amide compound and use thereof as an MMP-13 inhibitor | TAKEDA PHARMACEUTICAL (JP) | 2007-06-06 | — | — | CN | disclosed |
| CN-1447789-A | Compounds for treating alzheimer's disease | ELAN PHARM INC (US) | 2003-10-08 | — | — | CN | disclosed |
| CN-1058002-C | Method for treatment of mixture of hydroperoxide | SUMITOMO CHEMICAL CO (JP) | 2000-11-01 | — | — | CN | disclosed |
| CN-1128754-A | Method for treatment of mixture of hydroperoxide | SUMITOMO CHEMICAL CO (JP) | 1996-08-14 | — | — | CN | disclosed |