Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014452 | 1.00 | TAAR1 (0.60) | TAAR1TRPA1AOC3SLC6A2MAOA | |
| SCHEMBL4433686 | 1.00 | TAAR1 (0.60) | TAAR1TRPA1AOC3SLC6A2MAOA | |
| SCHEMBL3672929 | 0.85 | TRPA1 (0.67) | TAAR1TRPA1AOC3SLC6A3RIPK1 | |
| Hydrochloric Acid SCHEMBL10535795 | 0.84 | TAAR1 (0.58) | TAAR1TRPA1AOC3RIPK1ADRA2A | |
| SCHEMBL18266052 | 0.84 | TAAR1 (0.58) | TAAR1TRPA1AOC3RIPK1 | |
| SCHEMBL7678158 | 0.83 | TAAR1 (0.50) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL9233371 | 0.82 | TAAR1 (0.56) | TAAR1TRPA1AOC3RIPK1ADRA2A | |
| SCHEMBL7691241 | 0.82 | TRPA1 (0.59) | TAAR1TRPA1AOC3RIPK1ADRA2A | |
| SCHEMBL13335229 | 0.81 | TRPA1 (0.63) | TAAR1TRPA1AOC3RIPK1ADRA2A | |
| SCHEMBL11415966 | 0.81 | TAAR1 (0.48) | TAAR1SLC6A2MAOASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4525865-A1 | CRYSTALLINE FORMS OF AN ESTROGEN RECEPTOR ANTAGONIST | Olema Pharmaceuticals, Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2023225354-A1 | CRYSTALLINE FORMS OF AN ESTROGEN RECEPTOR ANTAGONIST | OLEMA PHARMACEUTICALS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |