SCHEMBL27360133

SCHEMBL27360133

O=C(CC(=O)C(=O)O)OCl

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 2/20 0.36
FEN1 P39748 11/20 0.35
ERCC5 P28715 10/20 0.35
PTPN1 P18031 1/20 0.34
MAPK1 P28482 1/20 0.33
SLC13A3 Q8WWT9 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
HAO1 Q9UJM8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3985200 0.78
SCHEMBL28005454 0.78 MGAM (0.32)
SCHEMBL9158669 0.77
SCHEMBL27658950 0.77 OR51E2 (0.40) OR51E2FEN1ERCC5PTPN1MAPK1
SCHEMBL27957079 0.76 MGAM (0.38)
SCHEMBL28035285 0.74 OR51E2 (0.38) OR51E2FEN1ERCC5PTPN1MAPK1
SCHEMBL11487172 0.74 MGAM (0.52) OR51E2FEN1ERCC5PTPN1MAPK1
SCHEMBL28519603 0.74 MGAM (0.35) OR51E2FEN1ERCC5PTPN1MAPK1
SCHEMBL13393789 0.73 TSHR (0.33)
Ethane SCHEMBL6211615 0.72 LDHA (0.42) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109384714-A The recovery method and production method of substituted or unsubstituted 2,3- pyridinedicarboxylic acid 北京颖泰嘉和生物科技股份有限公司 2019-02-26 CN disclosed
CN-206033630-U Device of production ethyl pyridine dicarboxylic acid diacetate 潍坊先达化工有限公司 2017-03-22 CN disclosed
CN-1057456-A Prepare pyridine-2 by the dichloro-dialkyl maleate, the method for 3-dicarboxylic acid dialkyl esters and derivative thereof AMERICAN CYANAMID CO (US) 1992-01-01 CN disclosed