Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.68 |
| ▸ | CCND1 | P24385 | 20/20 | 0.68 |
| ▸ | CCNA2 | P20248 | 12/20 | 0.68 |
| ▸ | CDK2 | P24941 | 12/20 | 0.68 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.68 |
| ▸ | FGFR2 | P21802 | 10/20 | 0.68 |
| ▸ | FGFR4 | P22455 | 10/20 | 0.68 |
| ▸ | FGFR3 | P22607 | 10/20 | 0.68 |
| ▸ | CCND2 | P30279 | 8/20 | 0.67 |
| ▸ | CCND3 | P30281 | 8/20 | 0.67 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.67 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360176 | 0.89 | CDK4 (0.55) | CDK4CCND1CCNA2CDK2FGFR1 | |
| SCHEMBL29991330 | 0.89 | CDK4 (0.55) | CDK4CCND1CCNA2CDK2FGFR1 | |
| SCHEMBL25122954 | 0.89 | CDK4 (0.55) | CDK4CCND1CCNA2CDK2FGFR1 | |
| SCHEMBL27360237 | 0.88 | TTK (0.54) | CDK4CCND1CCNA2CDK2FGFR1 | |
| SCHEMBL27360012 | 0.86 | CDK4 (0.52) | CDK4CCND1CCNA2CDK2FGFR1 | |
| SCHEMBL27358291 | 0.84 | CCND1 (0.51) | CDK4CCND1CCNA2CDK2FGFR1 | |
| SCHEMBL27360177 | 0.83 | TTK (0.49) | CDK4CCND1CCNA2CDK2FGFR1 | |
| SCHEMBL30883462 | 0.83 | CCND1 (0.51) | CDK4CCND1CCNA2CDK2FGFR1 | |
| SCHEMBL27225511 | 0.83 | CCND1 (0.51) | CDK4CCND1CCNA2CDK2FGFR1 | |
| SCHEMBL27358626 | 0.82 | CCND1 (0.54) | CDK4CCND1CCNA2CDK2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039903-A2 | CDK2 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |