Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.60 |
| ▸ | DRD3 | P35462 | 9/20 | 0.60 |
| ▸ | HTR1A | P08908 | 9/20 | 0.60 |
| ▸ | HTR2A | P28223 | 8/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.60 |
| ▸ | DRD1 | P21728 | 3/20 | 0.60 |
| ▸ | DRD5 | P21918 | 3/20 | 0.60 |
| ▸ | HRH1 | P35367 | 4/20 | 0.57 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011318 | 0.91 | DRD2 (0.69) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL16218814 | 0.89 | MAPT (0.56) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL7653085 | 0.88 | CYP2D6 (0.70) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL3197906 | 0.86 | CYP2D6 (0.63) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL5178761 | 0.84 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL2095204 | 0.84 | DRD2 (0.58) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL10661045 | 0.84 | DRD2 (0.58) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL8223307 | 0.84 | KDM4E (0.62) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL8334022 | 0.84 | DRD2 (0.58) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL14320563 | 0.84 | MAPT (0.59) | DRD2DRD3HTR1AHTR2ATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1281854-A | Benzothiazine derivative | SUNTORY LTD (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1058492-C | benzothiazine derivatives | SUNTORY LTD (JP) | 2000-11-15 | — | — | CN | disclosed |
| CN-1119859-A | benzothiazine derivatives | SUNTORY LTD (JP) | 1996-04-03 | — | — | CN | disclosed |