Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
| ▸ | AGT | P01019 | 2/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 11/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854283 | 0.94 | AGTR1 (0.45) | AGTR1AGTR2AGTLTB4R2RXFP1 | |
| SCHEMBL27362689 | 0.90 | AGTR1 (0.39) | AGTR1AGTR2AGTLTB4R2 | |
| SCHEMBL9854268 | 0.83 | AGTR1 (0.43) | AGTR1AGTR2AGTLTB4R2 | |
| SCHEMBL9854287 | 0.80 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9591475 | 0.78 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL5180024 | 0.76 | AGTR1 (0.53) | AGTR1AGTR2AGTLTB4R2 | |
| SCHEMBL29205122 | 0.74 | AGTR1 (0.54) | AGTR1AGTR2AGTLTB4R2 | |
| SCHEMBL29205124 | 0.74 | AGTR1 (0.54) | AGTR1AGTR2AGTLTB4R2 | |
| SCHEMBL5789793 | 0.73 | AGTR1 (0.41) | AGTR1AGTR2AGTLTB4R2 | |
| SCHEMBL9854356 | 0.72 | LTB4R2 (0.48) | AGTR1AGTR2LTB4R2RXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051358-A | Condensed imdazole derivatives and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-05-15 | — | — | CN | disclosed |