Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 2/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11972565 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL20519453 | 0.84 | GBA1 (0.46) | CA2CA4GBA1GNAI3GNAO1 | |
| SCHEMBL13543169 | 0.84 | HRH2 (0.52) | CA2CA4HRH2HRH1HRH3 | |
| SCHEMBL3249860 | 0.84 | HRH2 (0.52) | CA2CA4HRH2HRH1HRH3 | |
| SCHEMBL8116676 | 0.79 | GNAI3 (0.56) | HRH2HRH1HRH3GNAI3GNAO1 | |
| SCHEMBL6176615 | 0.79 | GNAI3 (0.56) | HRH2HRH1HRH3GNAI3GNAO1 | |
| SCHEMBL23023305 | 0.78 | GBA1 (0.37) | CA2CA4GBA1HRH3GLB1 | |
| SCHEMBL20698402 | 0.78 | GBA1 (0.44) | HRH2HRH1GBA1HRH3GLB1 | |
| SCHEMBL19174517 | 0.78 | EHMT2 (0.38) | CA2CA4GBA1HRH3GLB1 | |
| SCHEMBL17284198 | 0.78 | GBA1 (0.34) | CA2CA4HRH2HRH1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039858-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |