Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345960 | 0.77 | SCN4A (0.47) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5667704 | 0.77 | NISCH (0.50) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL528245 | 0.74 | MAPK9 (0.54) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| Benzene SCHEMBL27839441 | 0.74 | MAPK9 (0.54) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1345719 | 0.74 | CYP3A4 (0.40) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL24228161 | 0.73 | TAAR1 (0.38) | L3MBTL1AKT1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27683877 | 0.73 | MAPK9 (0.53) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29040464 | 0.73 | MAPK9 (0.53) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28405187 | 0.72 | PARP1 (0.52) | CYP1A2CYP2C9CYP2C19NPC1RAB9A | |
| SCHEMBL21141810 | 0.70 | BRD4 (0.45) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067684-C | Imidazo [1,5-1] quinolines for treatment of anxiety and sleep disorders | PHAMACIA UPJOHN CO (US) | 2001-06-27 | — | — | CN | claimed |
| CN-1135753-A | Imidazo [1, 5-a ] quinolines for the treatment of anxiety and sleep disorders | UPJOHN CO (US) | 1996-11-13 | — | — | CN | claimed |
| CN-1067684-C | Imidazo [1,5-1] quinolines for treatment of anxiety and sleep disorders | PHAMACIA UPJOHN CO (US) | 2001-06-27 | — | — | CN | disclosed |
| CN-1135753-A | Imidazo [1, 5-a ] quinolines for the treatment of anxiety and sleep disorders | UPJOHN CO (US) | 1996-11-13 | — | — | CN | disclosed |