SCHEMBL27360697

SCHEMBL27360697

O=S(=O)(C=CNc1ccccc1)C=CNc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
CA2 P00918 4/20 0.41
CA1 P00915 3/20 0.41
KEAP1 Q14145 2/20 0.41
KMT2A Q03164 2/20 0.40
CA4 P22748 2/20 0.40
CA9 Q16790 2/20 0.40
IL1RN P18510 1/20 0.40
ERAP1 Q9NZ08 1/20 0.40
PKM P14618 2/20 0.39
IDO1 P14902 1/20 0.39
MEN1 O00255 1/20 0.38
TLR9 Q9NR96 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9736486 0.83 NPC1 (0.48) ALDH1A1NPC1RAB9ANFKB1NFKB2
SCHEMBL9736491 0.83 NPC1 (0.48) ALDH1A1NPC1RAB9ANFKB1NFKB2
SCHEMBL22714095 0.83 ALDH1A1 (0.48) ALDH1A1NPC1RAB9ANFKB1NFKB2
Hydrochloric Acid SCHEMBL9735235 0.81 NPC1 (0.47) ALDH1A1NPC1RAB9ANFKB1NFKB2
Hydrochloric Acid SCHEMBL9735236 0.81 NPC1 (0.47) ALDH1A1NPC1RAB9ANFKB1NFKB2
SCHEMBL223592 0.77 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ANFKB1NFKB2
SCHEMBL223591 0.77 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ANFKB1NFKB2
SCHEMBL27468347 0.75 ALDH1A1 (0.39) ALDH1A1NPC1RAB9ANFKB1NFKB2
SCHEMBL11331899 0.72
Benzene SCHEMBL10426584 0.70 ALDH1A1 (0.52) ALDH1A1NPC1RAB9ANFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1067419-C Reactive dyestuffs their preparation and their use BAYER AG (DE) 2001-06-20 CN disclosed
CN-1106845-A Reactive dyestuffs their preparation and their use BAYER AG (DE) 1995-08-16 CN disclosed