SCHEMBL27361706

SCHEMBL27361706

NC(=O)Cc1c(C2CC2)n(CCc2ccccc2)c2ccc(O)cc12

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7962828 0.89 PLA2G2A (1.00) PLA2G2A
SCHEMBL27379318 0.82 PLA2G2A (0.61) PLA2G2A
SCHEMBL27360541 0.82 PLA2G2A (0.79) PLA2G2A
SCHEMBL27379322 0.81 PLA2G2A (0.80) PLA2G2A
SCHEMBL7963397 0.75 PLA2G2A (1.00) PLA2G2A
SCHEMBL7963009 0.74 PLA2G2A (0.76) PLA2G2A
SCHEMBL27452759 0.73 PLA2G2A (0.79) PLA2G2A
SCHEMBL2001561 0.73 PLA2G2A (0.64) PLA2G2A
SCHEMBL7965308 0.73 PLA2G2A (0.74) PLA2G2A
SCHEMBL7952628 0.73 PLA2G2A (1.00) PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1068588-C 1H-indole-3-acetamide splA2 inhibitors LILLY CO ELI (US) 2001-07-18 CN disclosed
CN-1098715-A PLA 2 inhibitors 1H-indole-3-acetamide compounds LILLY CO ELI (US) 1995-02-15 CN disclosed