Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 6/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.33 |
| ▸ | CDK2 | P24941 | 5/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND2 | P30279 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25123909 | 0.78 | PIM1 (0.37) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL29991127 | 0.78 | PIM1 (0.37) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL31073291 | 0.78 | CDK2 (0.56) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL25123908 | 0.76 | CCND1 (0.39) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL30872552 | 0.76 | CCND1 (0.39) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL5265428 | 0.75 | CDK4 (0.52) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL30837281 | 0.72 | CSNK1D (0.30) | — | |
| SCHEMBL30837301 | 0.72 | — | — | |
| SCHEMBL16071689 | 0.72 | FGFR1 (0.44) | — | |
| SCHEMBL30837273 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039903-A2 | CDK2 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |