Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360989 | 0.85 | HDAC6 (0.57) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12472237 | 0.81 | HDAC6 (1.00) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL27360994 | 0.79 | HDAC6 (0.52) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL3635237 | 0.78 | TSHR (0.54) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL8241462 | 0.77 | HDAC1 (0.69) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL5020665 | 0.77 | HDAC1 (1.00) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL12850618 | 0.77 | HDAC1 (0.79) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL1367947 | 0.76 | HDAC6 (1.00) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL4930132 | 0.75 | HDAC1 (0.76) | HDAC6HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL1986357 | 0.74 | HDAC1 (0.96) | HDAC6HDAC1HDAC8HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028654-A2 | HISTONE DEACETYLASE INHIBITORS AND USE OF THE SAME | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-02-08 | — | — | WO | disclosed |