Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612527 | 0.89 | CYP2C19 (0.55) | TSHRALDH1A1SLC6A2SLC6A3ADRA2B | |
| SCHEMBL12124877 | 0.89 | TSHR (0.50) | TSHRALDH1A1SLC6A2SLC6A3ADRA2B | |
| SCHEMBL3160936 | 0.88 | MAOB (0.52) | TSHRALDH1A1SLC6A2SLC6A3ADRA2B | |
| SCHEMBL19797774 | 0.87 | TAAR1 (0.61) | ALDH1A1KCNH2OPRK1SIGMAR1HRH3 | |
| SCHEMBL10746744 | 0.87 | AOC3 (0.47) | TSHRALDH1A1SLC6A2SLC6A3ADRA2B | |
| SCHEMBL170943 | 0.85 | BCHE (0.51) | TSHRALDH1A1SLC6A2SLC6A3ADRA2B | |
| SCHEMBL13995625 | 0.83 | SIGMAR1 (0.47) | TSHRALDH1A1SLC6A2SLC6A3ADRA2B | |
| SCHEMBL9111670 | 0.83 | KMT2A (0.50) | TSHRALDH1A1SLC6A2SLC6A3ADRA2B | |
| SCHEMBL9110973 | 0.83 | TSHR (0.62) | TSHRALDH1A1SLC6A2SLC6A3ADRA2B | |
| SCHEMBL13673936 | 0.83 | TSHR (0.54) | TSHRALDH1A1SLC6A2SLC6A3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004286-B1 | BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS | CYALUME TECH INC (US) | 2019-08-28 | — | — | EP | claimed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-11779912-B2 | Synthesis and characterization of Ru alkylidene complexes | UMICORE AG & CO. KG (DE) | 2023-10-10 | — | — | US | disclosed |
| US-20230285573-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2023-09-14 | — | — | US | disclosed |
| US-20230285573-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2023-09-14 | — | — | US | disclosed |
| US-20230165854-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | SHOUTI INC. | 2023-06-01 | — | — | US | disclosed |
| US-20230165854-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | SHOUTI INC. | 2023-06-01 | — | — | US | disclosed |
| US-20230025327-A1 | CONJUGATES OF TUBULYSIN DERIVATIVES AND CELL BINDING MOLECULES AND METHODS OF MAKING | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
| US-11535643-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-12-27 | — | — | US | disclosed |
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| US-20070249678-A1 | SYNTHESIS AND USES OF PYROGLUTAMIC ACID DERIVATIVES | PRODIMED, S.A. (ES) | 2007-10-25 | — | — | US | disclosed |
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-0196484-B1 | PRESSURE SENSITIVE MANIFOLD SHEET | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4704379-A | Pressure sensitive manifold sheet | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1987-11-03 | — | — | US | disclosed |
| EP-0196484-A1 | Pressure sensitive manifold sheet | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4120957-A | ANTHELMINTICS | ROHM AND HAAS COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249678-A1 | SYNTHESIS AND USES OF PYROGLUTAMIC ACID DERIVATIVES | GLUL, RIMKLA, PHKG1 | TSHR 2830/4885ALDH1A1 3368/4885SLC6A2 4818/4885 |
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | TSHR 1050/4885ALDH1A1 982/4885SLC6A2 81/4885 |
| US-20230285573-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | NEDD4, CBL, UBQLN2 | TSHR 3408/4885ALDH1A1 4642/4885SLC6A2 925/4885 |
| US-11535643-B2 | Macrolides with modified desosamine sugars and uses thereof | FUT6, MGAM, B3GNT2 | TSHR 3186/4885ALDH1A1 3204/4885SLC6A2 4389/4885 |
| US-20230025327-A1 | CONJUGATES OF TUBULYSIN DERIVATIVES AND CELL BINDING MOLECULES AND METHODS OF MAKING | TEK, TEKT1, EPCAM | TSHR 1675/4885ALDH1A1 3961/4885SLC6A2 1327/4885 |
| US-11779912-B2 | Synthesis and characterization of Ru alkylidene complexes | PORCN, ORC3, COASY | TSHR 4008/4885ALDH1A1 1478/4885SLC6A2 4353/4885 |
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | PREP, PEPD, DPP4 | TSHR 2555/4885ALDH1A1 1180/4885SLC6A2 4281/4885 |
| US-20230165854-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | APLNR, AGTR1, AGTR2 | TSHR 1332/4885ALDH1A1 2722/4885SLC6A2 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.