Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397416 | 0.77 | HIF1A (0.43) | HIF1AMEN1LMNATHRBBLM | |
| SCHEMBL378249 | 0.75 | — | — | |
| SCHEMBL25731648 | 0.72 | CREBBP (0.45) | HIF1AMEN1KMT2APIM1PIM3 | |
| SCHEMBL31175932 | 0.72 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL249552 | 0.72 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL15647800 | 0.70 | ADRA1A (0.40) | HIF1AMEN1LMNATHRBBLM | |
| SCHEMBL31588841 | 0.70 | KMT2A (0.67) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL27511393 | 0.70 | KMT2A (0.67) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL1547476 | 0.69 | TDP1 (0.52) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL612984 | 0.69 | BRD4 (0.53) | BRD4XDHCHRNB1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1069315-C | Process for prepn. of 1,3-dimethyl-5-fluoro-pyrazole-4-carboxanilides | BAYER AG (DE) | 2001-08-08 | — | — | CN | disclosed |
| CN-1161329-A | Process for prepn. of 1,3-dimethyl-5-fluoro-pyrazole-4-carboxanilides | BAYER AG (DE) | 1997-10-08 | — | — | CN | disclosed |