Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27178719 | 0.82 | CRBN (0.43) | CRBNDDB1GAA | |
| SCHEMBL23066000 | 0.81 | CRBN (0.50) | ALDH1A1KDM4EHPGDCRBNDDB1 | |
| SCHEMBL27179079 | 0.79 | CRBN (0.40) | ALDH1A1CRBNDDB1MEN1KMT2A | |
| SCHEMBL30738817 | 0.79 | CRBN (0.40) | ALDH1A1CRBNDDB1MEN1KMT2A | |
| SCHEMBL27114789 | 0.77 | DDB1 (0.46) | ALDH1A1KDM4EHPGDCRBNDDB1 | |
| SCHEMBL27274660 | 0.77 | CRBN (0.46) | ALDH1A1KDM4EHPGDCRBNDDB1 | |
| SCHEMBL22857611 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDCRBNDDB1 | |
| SCHEMBL25653902 | 0.76 | CRBN (0.48) | KDM4ECRBNDDB1GAA | |
| SCHEMBL30738835 | 0.74 | FFAR4 (0.37) | ALDH1A1KDM4ECRBNDDB1MEN1 | |
| SCHEMBL30475457 | 0.74 | DDB1 (0.48) | ALDH1A1KDM4ECRBNDDB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026083-A1 | TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY | RIBON THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |