Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18127944 | 0.85 | CA12 (0.53) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL25318790 | 0.82 | MEN1 (0.57) | PHLPP2ALDH1A1MAPTHRH3SCN1A | |
| SCHEMBL22423696 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL11770958 | 0.79 | PHLPP2 (0.49) | PHLPP2ALDH1A1MAPTCHRM1CHRM2 | |
| SCHEMBL6068040 | 0.79 | TSHR (0.59) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL22407682 | 0.79 | CA12 (0.47) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL570471 | 0.77 | CA12 (0.70) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL11839195 | 0.77 | TSHR (0.61) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL28245601 | 0.77 | ALDH1A1 (0.63) | PHLPP2ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL18675999 | 0.76 | TDP1 (0.46) | ALDH1A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |