Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524443 | 0.95 | MAPT (0.39) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7320459 | 0.88 | MAPT (0.42) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7312983 | 0.83 | MAPT (0.42) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7395942 | 0.83 | MAPT (0.42) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7388905 | 0.80 | MAPT (0.42) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7395083 | 0.76 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7392907 | 0.76 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7395949 | 0.76 | SMN1; SMN2 (0.33) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7396723 | 0.76 | SMN1; SMN2 (0.33) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Ethyl Acetate SCHEMBL27527286 | 0.74 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1062266-C | Amidine derivative and platelet agglutination inhibitor containing said amidine derivative | SCHERING CORP (DE) | 2001-02-21 | — | — | CN | disclosed |
| CN-1154962-A | Amidine derivative and platelet agglutination inhibitor containing said amidine derivative | MITSUI TOATSU CHEMICALS (JP) | 1997-07-23 | — | — | CN | disclosed |