Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392907 | 0.97 | MAPT (0.43) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7318811 | 0.95 | MAPT (0.43) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7311917 | 0.92 | MAPT (0.43) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7392480 | 0.88 | ITGB3 (0.33) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7320459 | 0.87 | MAPT (0.42) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7312983 | 0.87 | MAPT (0.42) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7316347 | 0.87 | MCHR1 (0.33) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7392925 | 0.86 | ITGB3 (0.47) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7392924 | 0.86 | ITGB3 (0.47) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7395082 | 0.85 | ITGB3 (0.51) | ALDH1A1RAB9ASMN1; SMN2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |