Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.59 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.59 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.56 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.53 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007614 | 1.00 | GRIK1 (0.59) | GRIK1GRIK2NOD1MAPTKMT2A | |
| SCHEMBL28007955 | 1.00 | GRIK1 (0.59) | GRIK1GRIK2NOD1MAPTKMT2A | |
| SCHEMBL28007603 | 1.00 | GRIK1 (0.59) | GRIK1GRIK2NOD1MAPTKMT2A | |
| SCHEMBL28921485 | 1.00 | GRIK1 (0.59) | GRIK1GRIK2NOD1MAPTKMT2A | |
| SCHEMBL28818201 | 1.00 | GRIK1 (0.59) | GRIK1GRIK2NOD1MAPTKMT2A | |
| SCHEMBL27403984 | 0.96 | NOD1 (0.57) | GRIK1GRIK2NOD1MAPTKMT2A | |
| SCHEMBL17537076 | 0.93 | NOD1 (0.59) | GRIK1GRIK2NOD1MAPTKMT2A | |
| SCHEMBL23531056 | 0.90 | GRIK1 (0.69) | GRIK1GRIK2NOD1MAPTSLC1A2 | |
| SCHEMBL1960725 | 0.90 | GRIK1 (0.69) | GRIK1GRIK2NOD1MAPTSLC1A2 | |
| SCHEMBL3696618 | 0.90 | GRIK1 (0.69) | GRIK1GRIK2NOD1MAPTSLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040245-A1 | PEPTIDE DERIVATIVES AND RELATED USES AS OREXIN AGONISTS | CENTESSA PHARMACEUTICALS (OREXIA) LIMITED (GB) | 2024-02-22 | — | — | WO | disclosed |