Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.65 |
| ▸ | NQO1 | P15559 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363117 | 0.92 | KMT2A (0.66) | MAPTALDH1A1NPC1SMN1; SMN2TP53 | |
| SCHEMBL4724848 | 0.92 | MAPT (0.69) | MAPTALDH1A1NPC1SMN1; SMN2TP53 | |
| SCHEMBL12186489 | 0.91 | TDP1 (0.68) | MAPTALDH1A1NPC1SMN1; SMN2TP53 | |
| SCHEMBL4720351 | 0.90 | MAPT (0.68) | MAPTALDH1A1NPC1SMN1; SMN2TP53 | |
| SCHEMBL4720540 | 0.88 | MAPT (0.59) | MAPTALDH1A1NPC1SMN1; SMN2TP53 | |
| SCHEMBL9668818 | 0.88 | MAPT (0.53) | MAPTALDH1A1NPC1SMN1; SMN2TP53 | |
| SCHEMBL11503962 | 0.87 | MAPT (0.65) | MAPTALDH1A1NPC1SMN1; SMN2TP53 | |
| SCHEMBL2155052 | 0.87 | ADRB1 (0.66) | MAPTALDH1A1NPC1SMN1; SMN2TP53 | |
| SCHEMBL4143515 | 0.87 | MAPT (0.56) | MAPTALDH1A1NPC1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL27915382 | 0.87 | MAPT (0.57) | MAPTALDH1A1NPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056840-C | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2000-09-27 | — | — | CN | disclosed |
| CN-1143639-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1997-02-26 | — | — | CN | disclosed |